Chang Liu

Ph.D. student in the Machine Learning Department at Carnegie Mellon University, advised by Prof. Artur Dubrawski.

Portrait of Chang Liu

Research

Democratizing expertisein hospitals, and foundation models.

Affordable outbreak detection

Detecting hospital outbreaks with multimodal models trained on routinely available multimodal data: MALDI-TOF mass spectra, antimicrobial resistance profiles, and electronic health records. The aim is to reduce dependency on the whole-genome sequencing gold standard, so that specialist-grade detection stays affordable for every hospital.

Self-improving open models

Improving LLM reasoning through better extraction and use of experiential abstractions, via in-context learning or post-training. The aim is to distill expert tips and past trajectories in the form of abstractions into open-source models and allow self-improvement.

Education

  • 2023 — 2028 (est.)Pittsburgh, US

    Ph.D., Machine Learning

    Carnegie Mellon University, School of Computer Science

  • 2019 — 2023Beijing, China

    B.Eng., Computer Science

    Tsinghua University — Yao Class, Institute for Interdisciplinary Information Sciences · GPA 3.91/4.00

Industry

  • 05/2026 — 08/2026San Jose, US

    Research Intern, Video Recommendation

    TikTok

    Modeling user preference over professionally generated content (PGC) to improve recommendation performance.

Publications

  • EMNLP · under reviewMay 2026

    Notes to Self: Can LLMs Benefit from Experiential Abstractions?

    Chang Liu, Xinyu Li, Artur Dubrawski*

  • AMIA Annual SymposiumMay 2026

    Towards Practical Multimodal Outbreak Detection

    Chang Liu, Jieshi Chen, Alexander J. Sundermann, Kathleen Shutt, Marissa P. Griffith, Lora Lee Pless, Lee H. Harrison, Artur Dubrawski*

  • AMIA Amplify Informatics ConferenceFeb 2026

    Exploring the Utility of MALDI-TOF Mass Spectrometry and Antimicrobial Resistance in Hospital Outbreak Detection

    Chang Liu, Jieshi Chen, Alexander J. Sundermann, Kathleen Shutt, Marissa P. Griffith, Lora Lee Pless, Lee H. Harrison, Artur Dubrawski*

  • NeurIPS 2025 Workshop · LLM EvalSep 2025

    Depth as a Scaling Vector: Simple Pruning and Evaluation of Emergent Abilities in Pruned LLMs

    Chang Liu†, Arjun Choudhry†, Yifu Cai, Nina Żukowska, Mononito Goswami, Artur Dubrawski

  • NeurIPS 2025 Workshop · Efficient ReasoningSep 2025

    LayerMerge: Modality-Agnostic Depth Pruning for Efficient Foundation Model Deployment

    Arjun Choudhry†, Chang Liu†, Nina Żukowska, Yifu Cai, Mononito Goswami, Artur Dubrawski

  • NeurIPS 2025 Workshop · UniRepsSep 2025

    From Aggregation to Guidance: Strategies for Personalized Federated Fine-Tuning of Foundation Models

    Mikołaj Piórczyński, Wojciech Łapacz, Xinyu Li, Chang Liu, Abby Turner, Artur Dubrawski

  • CHIL 2025Apr 2025

    Bridging the Utility Gap Between MALDI-TOF and WGS for Affordable Outbreak Cluster Detection

    Chang Liu, Jieshi Chen, Lee H. Harrison, Artur Dubrawski*

  • arXiv preprintOct 2024

    Multimodal Structure Preservation Learning

    Chang Liu, Jieshi Chen, Lee H. Harrison, Artur Dubrawski*

  • PLOS Computational BiologyApr 2024

    A Probabilistic Knowledge Graph Approach for Target Identification

    Chang Liu†, Kaimin Xiao†, Cuinan Yu†, Yipin Lei†, … Dan Zhao*, Fengfeng Zhou*, Haidong Tang*, Jianyang Zeng*

  • Pacific Symposium on BiocomputingJan 2023

    Improving Target-disease Association Prediction through a Graph Neural Network with Credibility Information

    Chang Liu†, Cuinan Yu†, Yipin Lei†, … Dan Zhao*, Fengfeng Zhou*, Jianyang Zeng*

† equal contribution  ·  * corresponding author